Regenerative Skin Therapy at a Cellular Level
How it works
Clinically, polynucleotide treatments have been shown to improve skin elasticity and firmness by up to 30–40% over a course of treatments, while significantly enhancing hydration and reducing inflammation, making them particularly effective for delicate or compromised skin.
This advanced bio-stimulation supports tissue repair, strengthens the skin barrier, and improves overall skin integrity, resulting in a smoother, firmer, and more luminous complexion that continues to improve over time. Ideal for those seeking natural, long-term rejuvenation, Plinest® delivers subtle yet transformative results with minimal downtime, redefining skin health through intelligent, regenerative science.
Ideal For
- Fine lines
- Acne scarring
- Dark under-eye circles
- Skin laxity
- Poor tone and texture
- Neck, décolleté, inner arms and thighs, knees and intimate area rejuvenation
What treatments work well with polynucleotides?
Polynucleotides are highly versatile and can be combined with a range of advanced aesthetic treatments to enhance and prolong your results. As a regenerative treatment, they work by stimulating repair within the skin, making them an excellent partner to treatments that improve hydration, skin quality and collagen production.
Many of our patients achieve the most impressive results through our bespoke regenerative treatment plans, where treatments are carefully selected and combined to target their individual concerns. Rather than relying on a single treatment, this approach creates a synergistic effect, delivering healthier, stronger and more youthful-looking skin over time.
For patients seeking the ultimate regenerative skin rejuvenation, our Regenerative Reset Packages combine some of the most advanced treatments available, including polynucleotides, exosomes, skin remodelling treatments and energy-based technologies. These packages have been designed to maximise collagen stimulation, tissue repair and long-term skin health, providing exceptional results for patients looking to restore, rejuvenate and future-proof their skin.
Polynucleotides work particularly well alongside:
- Anti-wrinkle injections
- Dermal fillers
- Profhilo®
- Exosomes
- Skin boosters
- Energy-based treatments such as Exion™ and Axion®
By combining treatments, we can address multiple aspects of ageing including skin quality, hydration, volume loss, fine lines and tissue regeneration.
Prices
Course of three
£850
Per area
One Area Maintenance Treatment
£300
Single treatment
Frequently Asked Questions
What are polynucleotides?
Polynucleotides are highly purified molecules that work to repair and regenerate the skin by stimulating cellular activity and supporting tissue renewal.
How is Plinest® different from skin boosters?
Unlike traditional skin boosters that primarily hydrate, Plinest® actively repairs and rebuilds the skin, improving its structure and function over time.
What areas can be treated?
Plinest® is commonly used on the face, neck, décolletage, and under-eye area, particularly for delicate or ageing skin.
Is the treatment painful?
The treatment is well tolerated, with numbing used if required to ensure comfort throughout.
Is there any downtime?
Downtime is minimal, with small injection marks or slight swelling that typically settles within 24–48 hours.
How many treatments are needed?
A course of 2–3 treatments spaced a few weeks apart is usually recommended for optimal results.
When will I see results?
Results develop gradually as the skin regenerates, with noticeable improvements in texture, hydration, and firmness over several weeks.
Is it suitable for all skin types?
What are the main benefits?
Clients can expect improved skin quality, enhanced hydration, increased firmness, and a more radiant, youthful appearance.
Why choose Plinest®?
Plinest® offers a sophisticated, regenerative approach to ageing, focusing on long-term skin health and natural, refined results rather than temporary fixes.
Can you have anti-wrinkle injections and polynucleotides together?
Yes. Anti-wrinkle injections and polynucleotides work in different ways and complement each other beautifully. Anti-wrinkle injections soften expression lines by relaxing muscle movement, while polynucleotides improve skin quality, hydration and tissue repair. Together, they create a smoother, fresher and more rejuvenated appearance.
Can you have Profhilo® and polynucleotides together?
Yes. Profhilo® and polynucleotides are often combined as part of a regenerative treatment plan. Profhilo® delivers intense hydration and skin remodelling, while polynucleotides support cellular repair and collagen production. Used together, they can improve skin texture, firmness, elasticity and overall skin quality for enhanced rejuvenation results.